Blood Bank Zone

Blood Bank Management
Functions and requirements needs a bloodbank to manage are described here.. » read more..

• Introduction and Functions
• Need For Blood Bank
• Blood Bank Premises Design
• Space Requirement for Blood Transfusion Service
• Basic Equipments and Reagents
• Donor Recruitment and Motivations
• Donor Blood Collection
• Laboratory Techniques
• Documentation and Record Maintenance
• Continuing Education in Blood Transfusion
• Guidelines for clinical use of blood
• Consummables and equipment for bloodbank

Principles of Immunohaematology
The knowledge of basic concepts of immunology is essential in understanding the principles of immunohaematology which incorporate genetics, immunology, biochemistry and haematology » read more..

• Introduction
• Immunohaematology Reactions
• Reagents Used In Detecting Antigen-Antibody Reactions
• Factors Influencing Antigen-Antibody Reaction
• Complement System
• Genetics
• Blood Group Systems
• Blood Genetics & Biochemistry
• Importance of the other blood group systems
• Red Cell Serology

Red Cell Serology
Red cell serological reactions form the basis of laboratory testing in a blood transfusion service » read more..

• Red Cell Serology Introduction
• ABO Grouping
• Preparation of Red Cells for ABO Testing
• Blood grouping - Methods & Procedure
• Blood Grouping - Newer Techniques
• Reagents
• Rh Grouping
• Rh Genotyping
• Antiglobulin Test
• Enhancing Media for IAT
• Pretransfusion Testing (Compatibility Testing)
• Labelling and issue of Blood

Donor selection and Blood collection
Collection of blood is the most important function of a blood transfusion centre. If the procedure of donor selection and blood colection is carried out meticulously, it will assure a safe and adequate blood supply

• Donor Selection
• Conditions requiring permanent deferral
• Condtiions requiring temporary deferral
• Physical Assessment of Donors
• Preliminary Tests for Donor Selection
• Blood Collection
• Processing of donor blood
• Quality Control of Donor Selection and Blood Collection

Preservation Storage Transportation of Blood
The primary objective of preservation, storage and transportation of blood and blood components is to preserve the viability and function of each relevant constituent, prevent any physical changes of the blood constituent during storage and minimize bacterial growth

• Preservation Storage Transportation Introduction
• Anticoagulantion and Preservative
• Physical and Biochemical Effects of Storage
• Rejuvenation of Stored Red Cells
• Quality Control of Blood Storage
• Transportation of Blood and Blood Components

Blood Transfusion in Clinical Practice
Blood transfusion now plays an important role in comprehensive patient care in modern medicine. The support of patients with haematological disorders and tranplant surgery will not be possible without the use of blood transfusion..

• Blood Transfusion in Clinical Practice - Introduction
• Transfusion of Red Cells
• Platelet Transfusion
• Granulocyte Transfusion
• Transfusion of Plasma and its -Components
• Massive Blood Transfusion
• Haemostasis and component treatment
• Multiple Transfusions
• Autologous Blood Transfusion
• Practical Aspects of Administration of Blood

Quality Asssurance in Blood Transfusion Service
A simple definition of quality is ‘fitness for a purpose’. In blood transfusion service, the primary goal of quality is ‘transfusion of safe unit of blood.’ The objective is to ensure availability of a sufficient supply of blood, blood components of high quality with maximum efficacy and minimum risk to both donors and patients

• Quality Asssurance in Blood Transfusion Service - Introduction
• Standard Operating Procedures in Blood Banking
• Quality Control of Equipments
• Quality Control of Reagents
• Quality Assurance Process Monitoring

Trasfusion Transmitted Diseases
Transfusion of blood is not without risks. The most important hazard of blood transfusion is the risk of transmission of blood-borne infections. A knowledge of the infectious agents, with special emphasis on the diseases endemic in a particular region, is essential in understanding the strategies to prevent the transmission of these infections

• Transfusion Transmitted Diseases - Introduction
• Transfusion Transmitted Hepatitis
• Laboratory Diagnosis HBV Infection
• Prevention of Post-transfusion Viral_hepatitis B
• Acquired Immunodeficiency Syndrome (AIDS)
• Transmission of HIV infection
• Laboratory Diagnosis of HIV infection
• Laboratory Diagnosis of Syphilis
• Malaria
• Taxoplasmosis
• Bacterial Complications Of Transfusion

Transfusion Safety and Optimal Utilization of Blood
Transfusion is blood and blood components is associated with an inherent risk of transmission of blood-borne infections. Therefore, it is very important for a blood transfusion service to ensure a safe blood supply to the patients

• Safe Donors
• Safe Blood for Transfusion
• Safe Blood Products and Viral Inactivation Proceduresn
• Appropriate and Optimal Utilization of Blood

Adverse Reactions to Blood Transfusion
Transfusion of blood and blood components is usually a safe procedure however untoward effects of transfusion can occur frequently. A transfusion reaction is defined as any untoward event which occurs during or after transfusion of blood or blood components

• Transfusion Reactions
• Haemolytic Transfusion Reactions (HTR)
• Laboratory evaluation of suspected haemolytic reaction
• Non-haemolytic Immune Transfusion Reactions (NHTR)
• Transfusion related acute lung injury (TRALI) or Noncardiogenic pulomary oedema
• Non-immune Reactions
• Transfusion Risks

Antenatal and Neonatal Serology
Haemolytic disease of the newborn (HDN) is a condition in which the life span of the infant’s red cells is shortened by the action of antibodies derived from the mother by placental transfer. Antibodies in the mother are formed due to previous transfusion or by the entry of foetal red cells expressing paternally inherited antigens, into the maternal circulation.

• Haemolytic Disease of Newborn (HDN)
• Laboratory detection of Rh immunization
• Management of pregnancies at risk of HDN

Bloodbank regulations
Regulatory requirements of blood and/or its components including blood products in different countries