Bloodindex - Home
Search Bloodindex
Login Name :
Password :
 
 
 Dear Guest, Welcome to Bloodindex Sign in | Sign up



My health diary Health Diary - An Online Electronic Personal Health Record Solution

My health folder Health folder

Blood sugar diary Blood sugar diary

BP printable diary Blood pressure report charts and diary

Cholestrol diary Cholestrol Report Diary

Clinical tests diary Customizable Clinical Tests Diary

Treatment diary Treatment follow up diary

Directory service Directory Service

Knowledge zone knowledge Service

Download zone Download Center

Health calculators Health Calculators

News zone News Zone

Tell my friend Tell My Friend

Blood services Blood Services

Support services Download Center

Link map Download Center


Diabetes Zone - Comprehensive detailed information on Diabetes


My Health Folder


bloodindex AIDS zone


HIV/AIDS care community
You are here : Home Blood Zone T-lymphocyte count ( T cell counts )

T-lymphocyte count ( T cell counts )

T-lymphocyte count ( T cell counts )

This is a blood test that measures the number of T-lymphocytes (a type of white blood cell).

A T-cell count of may be helpful in the diagnosis of immunodeficiency diseases and lymphocytic diseases. It is also used to monitor how well therapy for these types of diseases is working.

Lymphocytes are white blood cells that are part of the immune system. T lymphocytes (T-cells) act directly (cellular immunity) to fight diseases or organisms, stimulate B lymphocytes (helper T-cells), or suppress some B lymphocyte functions (suppressor T-cells).


Blood Zone

About blood
About Blood Transfusion
Autologous Blood Transfusion
Effects of blood transfusion
Blood facts
Blood Diseases and Disorders
Eligibility test
Why many people don't donate blood
Blood Components
About Lymphocytes Cells
T-lymphocyte count ( T cell counts ) Test
Human immune system
Blood Donor Requirements
Blood Products
Blood Substitutes
Blood types
Apheresis
Q&A - Blood
Foods to increase your blood
Food to increase immunity
Rh Factor
What are Blood Groups
Health calendar
Glossary

Normal Values

Lymphocytes make up 16-45% of white blood cells. Of those lymphocytes, about half are T cells, a quarter are B cells, and another quarter are natural killer cells.

  • Helper T-cells, also known as absolute CD4+ or T4 count: more than 400 per microliter, or 32-68% of lymphocytes
  • Suppressor T-cells, also known as absolute CD8+ or T8 count: 150-1000 per microliter
Higher-than-normal T-cell levels may indicate:
  • Infectious mononucleosis (sometimes)
  • Multiple myeloma
  • Acute lymphocytic leukemia
Lower-than-normal T-cell levels may indicate:
  • Congenital T-cell deficiency (rare)
  • Congenital immunodeficiency disorders
  • Acquired immunodeficiency disorders
  • Leukemias
  • Cancer
  • Hodgkin's
  • Acute viral infection
  • Waldenstrom's macroglobulinemia
  • AIDS
  • Side effect of radiation therapy
  • Aging

How the test is performed

Blood is drawn from a vein on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood.

A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

For an infant or young child, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.

In the laboratory, the white blood cells are separated from the other blood cells. A stain or other substance that "labels" the cells is added to help identify which type of white blood cells are present.

B and T lymphocytes look the same under an ordinary microscope. However, they may be differentiated with an electron microscope. B or T lymphocytes may also be counted using immunofluorescence ( Immunofluorescence is a laboratory technique to identify specific antibodies or antigens ) or by flow cytometry. T cells can also be differentiated by the E rosette test (Blood is mixed with sheep red blood cells. The T cells will cling to the sheep cells and produce a distinctive rosette pattern).


Special considerations

This test can be affected by
  • Stress
  • Surgery
  • Chemotherapy medications
  • Corticosteroids
  • Immunosuppressive medications
  • X-rays
A flow cytometric measurement is more accurate than manual counts.

People with decreased T - lymphocytes may not react to diagnostic skin tests.

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.


See also Lymphocytes




Find nutrition values for common foods
 
Bloodindex - Blood pressure diary, reports and charts

Related pages

CD4(T-cell tests)

More Blood Tests

About Lymphocytes Blood Cells

Complete Bloodcount

Clinical Significance Tests and Normal Haematology Reference Values

 
 
 
Events | About us | Link to us | Contact us | Associates | Services | Fund-rising options | Feedback | Privacy policy | Disclaimer | RSS feed
© 2007 bloodindex